New reference intervals 2023
STEMDRL reference intervals for some trace element assays where updated on 1/3/23. This followed a review of the latest available literature and will ensure that, where possible, STEMDRL is harmonised with other UK Trace Elements Supra-Regional Assay Service (SAS) laboratories. Sources for these new reference intervals can be found via individual trace element pages (click on assay name below and then scroll down to reference range section).
Units Previous reference interval Reference interval from 1/3/23
Plasma Aluminium µmol/L <0.2 <0.4
Urine Arsenic nmol/mmol creat <30 <17
Blood Cadmium nmol/L <37 <17
Urine Cadmium nmol/mmol creat <1.0 <0.9
Blood Chromium nmol/L <40 <15
Urine Chromium nmol/mmol creat <6.1 <2.9
Blood Cobalt nmol/L <50 <10
Urine Cobalt nmol/mmol creat <1.6 <2.5
Blood Lead µmol/L <0.50 <0.10
Blood Mercury nmol/L <30 <25
Urine Mercury nmol/mmol creat <5 <1.4
We recommend following guidance developed with input from the SAS Trace Element group and the National Poisons Information Service (NPIS) when considering what action to take in response to a raised lead, mercury or arsenic result. The guidance can be found here. The following links from the guidance contain suggested action when a raised blood or urine result is found in a non-occupationally exposed individual:
Please also note blood lead will now be reported in µmol/L only and not in both µmol/L and µg/dL. If conversion to µg/dL is needed (e.g. when referring to the Health and Safety Executive Control of Lead at Work Regulations, 2002) please see use this conversion tool.
If there are any questions about these changes please contact STEMDRL.